Blanche of Castile served as regent of France on two occasions and held great power in the country even when she wasn’t ruling.
Blanche of Castile: France’s Indomitable Regent

Blanche of Castile served as regent of France on two occasions and held great power in the country even when she wasn’t ruling.
Berengaria of Navarre became Queen of England in the 1100s, but because her husband was always on crusade, she never got to settle down in England.
Joan I of Navarre was a regular queen. She became a country's first queen-regnant at the old age of one, then ran away to France with her mother, and made a happy political marriage.